⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16859351 | 0.79 | — | — | |
| SCHEMBL25000793 | 0.75 | — | — | |
| SCHEMBL376948 | 0.74 | — | — | |
| SCHEMBL13389955 | 0.70 | — | — | |
| SCHEMBL8084201 | 0.69 | — | — | |
| SCHEMBL16867309 | 0.69 | — | — | |
| SCHEMBL10582005 | 0.69 | — | — | |
| SCHEMBL9230585 | 0.69 | — | — | |
| SCHEMBL9723624 | 0.67 | — | — | |
| SCHEMBL3610101 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000893-A2 | PROCESS FOR PREPARING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREFOR | AstraZeneca AB (SE) | 2016-03-30 | — | — | EP | disclosed |
| EP-2894227-A2 | Process for preparing dipeptidyl peptidase iv inhibitors and intermediates therefor | AstraZeneca AB (SE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2894227-A2 | Process for preparing dipeptidyl peptidase iv inhibitors and intermediates therefor | AstraZeneca AB (SE) | 2015-07-15 | — | — | EP | disclosed |
| EP-2505579-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-11-05 | — | — | EP | disclosed |
| EP-2792672-A2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | AstraZeneca AB (SE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2505578-B1 | Methods and Compounds for Producing Dipeptidyl Peptidase IV Inhibitors and Intermediates thereof | ASTRAZENECA AB (SE) | 2014-09-24 | — | — | EP | disclosed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | disclosed |
| EP-2517706-B1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2014-06-25 | — | — | EP | disclosed |
| US-7420079-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-7420079-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| EP-1581487-A4 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1737970-A2 | PROCESS FOR PREPARING DIPEPTIDYL IV INHIBITORS AND INTERMEDIATES THEREFOR | Bristol-Myers Squibb Company (US) | 2007-01-03 | — | — | EP | disclosed |
| US-20050260712-A1 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2005-11-24 | — | — | US | disclosed |
| WO-2005106011-A2 | PROCESS FOR PREPARING DIPEPTIDYL IV INHIBITORS AND INTERMEDIATES THEREFOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |
| EP-1581487-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20050090539-A1 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | ASTRAZENECA AB (SE) | 2005-04-28 | — | — | US | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| EP-0808824-A2 | Process for preparing optically active 2-halogeno-3-hydroxypropionic acid ester | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |