Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EEF2K | O00418 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748948 | 0.90 | KMT2A (0.66) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL22982424 | 0.90 | KMT2A (0.66) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL19769226 | 0.89 | KMT2A (0.74) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL23009470 | 0.89 | KMT2A (0.67) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL22981925 | 0.88 | MAPT (0.58) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL29727500 | 0.86 | MAPT (0.59) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL23009440 | 0.86 | MAPT (0.59) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL4200490 | 0.83 | LIMK1 (0.69) | LIMK1ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL23009461 | 0.83 | LIMK1 (0.60) | LIMK1ALDH1A1KMT2AMEN1SYK | |
| SCHEMBL23009466 | 0.82 | LIMK1 (0.68) | LIMK1ALDH1A1KMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028919-A1 | METHODS AND COMPOSITIONS FOR PREVENTING SKIN TOXICITIES CAUSED BY BIOLOGICAL TARGETED CANCER DRUGS | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2021-02-18 | — | — | WO | disclosed |