Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | EEF2K | O00418 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22981954 | 0.90 | MEN1 (0.56) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL29924766 | 0.90 | MEN1 (0.56) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL4200490 | 0.83 | LIMK1 (0.69) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL23009459 | 0.83 | LIMK1 (0.66) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL4188528 | 0.79 | LIMK1 (0.63) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL22981955 | 0.79 | LIMK1 (0.38) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL4200595 | 0.77 | LIMK1 (0.70) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL4186923 | 0.76 | IKBKB (0.78) | LIMK1ALDH1A1EEF2KBRAFPDE4A | |
| SCHEMBL431577 | 0.76 | LIMK1 (1.00) | LIMK1ALDH1A1EEF2KLMNACYP1A2 | |
| SCHEMBL22982424 | 0.73 | KMT2A (0.66) | LIMK1ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028919-A1 | METHODS AND COMPOSITIONS FOR PREVENTING SKIN TOXICITIES CAUSED BY BIOLOGICAL TARGETED CANCER DRUGS | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2021-02-18 | — | — | WO | disclosed |