Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009512 | 0.89 | LMNA (0.66) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009464 | 0.88 | LMNA (0.64) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009520 | 0.88 | LMNA (0.64) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009471 | 0.88 | LMNA (0.64) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009516 | 0.88 | LMNA (0.53) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009521 | 0.86 | LMNA (0.62) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009518 | 0.84 | LMNA (0.60) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009519 | 0.81 | LMNA (0.67) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL23009511 | 0.78 | KMT2A (0.54) | LMNAMAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL13568370 | 0.78 | KDM4E (0.67) | LMNAMAPTKDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028919-A1 | METHODS AND COMPOSITIONS FOR PREVENTING SKIN TOXICITIES CAUSED BY BIOLOGICAL TARGETED CANCER DRUGS | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2021-02-18 | — | — | WO | disclosed |