SCHEMBL2301029

SCHEMBL2301029

C=C(C)C(=O)Oc1ccc(-c2cc(=O)c3cc(OC(=O)C(=C)C)ccc3o2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.60
TP53 P04637 6/20 0.60
NPC1 O15118 5/20 0.60
RAB9A P51151 5/20 0.60
KDM4E B2RXH2 4/20 0.60
ALDH1A1 P00352 4/20 0.60
CYP3A4 P08684 4/20 0.60
HPGD P15428 4/20 0.60
LMNA P02545 3/20 0.60
THRB P10828 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
NFKB1 P19838 2/20 0.60
NFKB2 Q00653 2/20 0.60
RELA Q04206 2/20 0.60
RXFP1 Q9HBX9 2/20 0.60
HSD17B10 Q99714 2/20 0.60
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18436555 0.94 MAPT (0.70) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL18468323 0.94 MAPT (0.68) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL9607679 0.94 MAPT (0.70) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL13609779 0.93 ABCB1 (0.65) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL19157960 0.92 MAPT (0.60) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL19881905 0.92 MAPT (0.60) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL18517353 0.92 MAPT (0.54) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL21091108 0.92 MAPT (0.68) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL20664349 0.91 MAPT (0.53) MAPTTP53NPC1RAB9AKDM4E
SCHEMBL18468341 0.91 MAPT (0.53) MAPTTP53NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306615-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
WO-2011160765-A1 POLYMERIZIBLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
WO-2011160764-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-12-29 WO disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 US disclosed
WO-2011098224-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2011-08-18 WO disclosed
WO-2011088882-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
WO-2011050893-A1 POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-05-05 WO disclosed
WO-2011035842-A1 POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed
WO-2010049044-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY VCL, LPXN, LCP1 MAPT 26/4885TP53 1366/4885NPC1 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.