⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28128554 | 0.82 | — | — | |
| SCHEMBL2727812 | 0.78 | — | — | |
| SCHEMBL2305065 | 0.77 | — | — | |
| SCHEMBL5789431 | 0.77 | — | — | |
| SCHEMBL1648363 | 0.77 | — | — | |
| SCHEMBL1142629 | 0.75 | — | — | |
| SCHEMBL5973868 | 0.75 | — | — | |
| SCHEMBL38662615 | 0.75 | — | — | |
| SCHEMBL22188679 | 0.75 | — | — | |
| SCHEMBL744087 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238175-A1 | SOLID STATE FORMS OF VENETOCLAX AND PROCESSES FOR PREPARATION OF VENETOCLAX | ASSIA CHEM IND LTD (IL) | 2021-08-05 | — | — | US | disclosed |
| US-11001582-B2 | Solid state forms of Venetoclax and processes for preparation of Venetoclax | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2021-05-11 | — | — | US | disclosed |
| US-20190135806-A1 | SOLID STATE FORMS OF VENETOCLAX AND PROCESSES FOR PREPARATION OF VENETOCLAX | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2019-05-09 | — | — | US | disclosed |
| CN-106164076-B | Compound as ROS1 inhibitor | 詹森药业有限公司 | 2019-03-26 | — | — | CN | disclosed |
| EP-3426655-A1 | SOLID STATE FORMS OF VENETOCLAX AND PROCESSES FOR PREPARATION OF VENETOCLAX | Assia Chemical Industries Ltd. (IL) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156398-A1 | SOLID STATE FORMS OF VENETOCLAX AND PROCESSES FOR PREPARATION OF VENETOCLAX | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2017-09-14 | — | — | WO | disclosed |
| EP-3160967-A1 | IMIDAZO[1,2-A]PYRAZIN-1YL-BENZAMIDE COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | F. Hoffmann-La Roche AG (CH) | 2017-05-03 | — | — | EP | disclosed |
| CN-105705500-A | Amide compounds for the treatment of HIV | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-105492008-A | Novel compounds and compositions for inhibition of fasn | FORMA THERAPEUTICS INC | 2016-04-13 | — | — | CN | disclosed |
| CN-102666545-B | As the heterocycle Pyrazolopyrimidine analogs of JAK inhibitor | CELLZOME LTD. (GB) | 2016-04-06 | — | — | CN | disclosed |
| CN-103153993-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2013-06-12 | — | — | CN | disclosed |
| CN-103119028-A | 1,2,4-Triazolone Derivative | TAISHO PHARMACEUTICAL CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-102947285-A | Sulfonamide derivatives as BCL-2-selective apoptosis inducers for the treatment of cancer and immune diseases | ABBOTT LAB | 2013-02-27 | — | — | CN | disclosed |
| EP-2350311-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010072712-A1 | BIARYL BENZYLAMINE DERIVATIVES | NOVARTIS AG (CH) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010056506-A1 | DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| EP-2044058-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007148070-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | disclosed |
| EP-1784388-A1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | AstraZeneca AB (SE) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021759-A1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2006-03-02 | — | — | WO | disclosed |