Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | POLD1 | P28340 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296337 | 0.97 | POLB (0.49) | POLBPOLA1POLD1 | |
| SCHEMBL2293561 | 0.94 | POLB (0.51) | POLBPOLA1POLD1 | |
| SCHEMBL20417783 | 0.92 | POLB (0.51) | POLBPOLA1POLD1 | |
| SCHEMBL12378786 | 0.91 | POLB (0.54) | POLBPOLA1POLD1 | |
| SCHEMBL18844329 | 0.91 | POLB (0.51) | POLBPOLA1POLD1 | |
| SCHEMBL14606222 | 0.91 | POLB (0.53) | POLBPOLA1POLD1 | |
| SCHEMBL15115325 | 0.90 | POLB (0.49) | POLBPOLA1POLD1 | |
| SCHEMBL17229171 | 0.90 | POLB (0.55) | POLBPOLA1POLD1 | |
| SCHEMBL20074268 | 0.90 | POLB (0.55) | POLBPOLA1POLD1 | |
| SCHEMBL304477 | 0.90 | POLB (0.55) | POLBPOLA1POLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758995-B2 | Solid phase sequencing of biopolymers | SEQUENOM, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110172111-A1 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | SEQUENOM, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7803529-B1 | Solid phase sequencing of biopolymers | SEQUENOM, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20060063193-A1 | Solid phase sequencing of double-stranded nucleic acids | TRUSTEES OF BOSTON UNIVERSITY, THE | 2006-03-23 | — | — | US | disclosed |
| US-6991903-B2 | Solid phase sequencing of double-stranded nucleic acids | SEQUENOM, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-0679196-B1 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM INC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030096258-A1 | Sequencing target nucleic acid; obtain single stranded nucleotide sequences, incubate with denatured nucleotide sequences, amplify determining sequence of nucleotide sequence | TRUSTEES OF BOSTON UNIVERSITY, THE | 2003-05-22 | — | — | US | disclosed |
| EP-1262564-A2 | Dna sequencing by mass spectrometry | SEQUENOM, INC. (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6436635-B1 | HYBRIDIZATION AND COMPLEXING WITH SINGLE-STRANDED NUCLEIC ACIDS; LIGATION TO PROBE; DISPLACEMENT POLYMERIZATION OF UNLIGATED STRAND; GENETIC ENGINEERING | BOSTON UNIVERSITY | 2002-08-20 | — | — | US | disclosed |
| US-6238871-B1 | HIGH SPEED; HIGH THROUGHPUT; NO REQUIRED ELECTROPHORESIS; SANGER SEQUENCING STRATEGY, THEN DETERMINING SEQUENCE BY ALIGNING TERMINATED FRAGMENTS ACCORDING TO MOLECULAR WEIGHT | SEQUENOM, INC. | 2001-05-29 | — | — | US | disclosed |
| US-6194144-B1 | GENERATING TWO TERMINATED NUCLEIC ACIDS; DETERMINATION MOLECULAR WEIGHT; CALIBRATION | SEQUENOM, INC. | 2001-02-27 | — | — | US | disclosed |
| US-6140053-A | DETERMINING A SEQUENCE OF A NUCLEIC ACID | SEQUENOM, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0830460-A1 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1997037041-A9 | DNA SEQUENCING BY MASS SPECTROMETRY | — | 1997-12-31 | — | — | WO | disclosed |
| US-5691141-A | SOLID PHASE SYNTHESIS, LINKING LARGE MOLECULES TO NUCLEOTIDES TO DIFFERENTIATE | SEQUENOM, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1997037041-A2 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM, INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1996032504-A2 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-10-17 | — | — | WO | disclosed |
| US-5547835-A | USING THE SANGER SEQUENCING STRATEGY AND ASSEMBLING THE SEQUENCE INFORMATION BY ANALYSIS OF THE NESTED FRAGMENTS OBTAINED BY BASE-SPECIFIC CHAIN TERMINATION VIA THEIR DIFFERENT MOLECULAR MASSES | SEQUENOM, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0679196-A1 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM, INC. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994016101-A2 | DNA SEQUENCING BY MASS SPECTROMETRY | KOESTER HUBERT (US) | 1994-07-21 | — | — | WO | disclosed |