SCHEMBL2301140

SCHEMBL2301140

O=C(O)C1=CC2=CC=CCN2C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7615185 0.98
Trifluoroacetic Acid SCHEMBL7644847 0.91
SCHEMBL2299288 0.91
SCHEMBL28317685 0.89
SCHEMBL18264400 0.85
Potassium Ion SCHEMBL3971393 0.84
Hydrochloric Acid SCHEMBL7406592 0.84
SCHEMBL2355110 0.75
SCHEMBL1008140 0.75
Hydrochloric Acid SCHEMBL16973350 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3435976-A1 ANTIBACTERIAL COMPOSITIONS Wockhardt Limited (IN) 2019-02-06 EP claimed
CN-109089413-A Bactericidal composition 沃克哈特有限公司 2018-12-25 CN claimed
WO-2018189575-A1 ANTIBACTERIAL COMPOSITIONS WOCKHARDT LIMITED (IN) 2018-10-18 WO claimed
CN-108289912-A The immunocyte and application thereof of immunity or inhibitive ability of immunity cell factor resistance with raising 先天肿瘤免疫公司 2018-07-17 CN claimed
CN-107580493-A Stable pharmaceutical composition comprising an antibacterial agent 沃克哈特有限公司 2018-01-12 CN claimed
EP-3236965-A1 STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENT Wockhardt Limited (IN) 2017-11-01 EP claimed
WO-2016181276-A1 STABLE PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIBACTERIAL AGENT WOCKHARDT LIMITED (IN) 2016-11-17 WO claimed
CN-103842361-A Pure S- -9-fluoro-6, 7-dihydro-8- (4-hydroxypiperidin-1-yl) -5-methyl-1-oxo-1H, -5H-benzo [ i, j ] quinolizine-2-carboxylic acid L-arginine salt tetrahydrate and preparation method thereof WOCKHARDT LTD 2014-06-04 CN claimed
CN-101500564-B Prodrugs of benzoquinolizine-2-carboxylic acid WOCKHARDT LTD 2012-07-25 CN claimed
CN-101220055-B Method for preparing fluoroquinolone compounds containing phosphoric acid ester group SHANGHAI YANGFAN MEDICINE TECHNOLOGY LTD 2011-09-07 CN claimed
EP-1509519-A1 CRYSTALLINE FLUOROQUINOLONE ARGININE SALT FORM Wockhardt Limited (IN) 2005-03-02 EP claimed
US-20030225119-A1 CRYSTALLINE FLUOROQUINOLONE ARGININE SALT FORM WOCKHARDT LIMITED 2003-12-04 US claimed
WO-2003099815-A1 CRYSTALLINE FLUOROQUINOLONE ARGININE SALT FORM WOCKHARDT LIMITED (IN) 2003-12-04 WO claimed
US-20030207908-A1 Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment WOCKHARDT LIMITED (IN) 2003-11-06 US claimed
EP-1305048-A2 INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES Wockhardt Limited (IN) 2003-05-02 EP claimed
WO-2002009758-A2 INHIBITORS OF CELLULAR EFFLUX PUMPS OF MICROBES WOCKHARDT LIMITED (IN) 2002-02-07 WO claimed
EP-1175217-A2 (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS Wockhardt Limited (IN) 2002-01-30 EP claimed
WO-2001085728-A2 ANTIBACTERIAL CHIRAL 8-(SUBSTITUTED PIPERIDINO)-BENZO [I, J] QUINOLIZINES, PROCESSES, COMPOSITIONS AND METHODS OF TREATMENT WOCKHARDT LIMITED (IN) 2001-11-15 WO claimed
WO-2000068229-A2 (S)-BENZOQUINOLIZINE CARBOXYLIC ACIDS AND THEIR USE AS ANTIBACTERIAL AGENTS WOCKHARDT LIMITED (IN) 2000-11-16 WO claimed
CN-86103954-A Preparation has the method for quinolone carboxylic acid ester's class of anti-microbial activity 1987-01-28 CN claimed