Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299903 | 0.94 | HSD11B1 (0.64) | HSD11B1 | |
| SCHEMBL2301388 | 0.82 | HSD11B1 (0.71) | HSD11B1 | |
| SCHEMBL2297875 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2303134 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2298979 | 0.78 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2300078 | 0.78 | HSD11B1 (0.70) | HSD11B1 | |
| SCHEMBL5445845 | 0.78 | HSD11B1 (0.70) | HSD11B1 | |
| SCHEMBL2300066 | 0.77 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL2299307 | 0.75 | HSD11B1 (0.65) | HSD11B1 | |
| SCHEMBL2299834 | 0.75 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998959-B2 | Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same | INCYTE CORPORATION (US) | 2011-08-16 | — | — | US | claimed |