Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.61 |
| ▸ | HPGD | P15428 | 13/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165939 | 0.87 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL23012520 | 0.87 | KDM4E (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL23034143 | 0.84 | MAPT (0.71) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL23033654 | 0.83 | MAPT (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28714614 | 0.82 | MAPT (0.52) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29479688 | 0.82 | MAPT (0.52) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL23033392 | 0.80 | MAPT (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29479820 | 0.80 | MAPT (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28707250 | 0.80 | NPC1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29479722 | 0.80 | NPC1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |