Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23034143 | 0.88 | MAPT (0.71) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL28698102 | 0.86 | MAPT (0.50) | MAPTKDM4EPTPN2PTPN1PTPN5 | |
| SCHEMBL28706300 | 0.85 | KDM4E (0.52) | MAPTKDM4EPTPN2PTPN1PTPN5 | |
| SCHEMBL31165939 | 0.85 | KDM4E (0.64) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL29479671 | 0.85 | KDM4E (0.52) | MAPTKDM4EPTPN2PTPN1PTPN5 | |
| SCHEMBL23012520 | 0.85 | KDM4E (0.64) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL23012299 | 0.84 | RAB9A (0.69) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL29479691 | 0.84 | HDAC6 (0.54) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL28701725 | 0.84 | HDAC6 (0.54) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL23033327 | 0.83 | MAPT (0.53) | MAPTKDM4EPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |