Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 5/20 | 0.45 |
| ▸ | MET | P08581 | 16/20 | 0.44 |
| ▸ | GRK2 | P25098 | 4/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479765 | 1.00 | GRK5 (0.45) | GRK5METGRK2PIM1PIM2 | |
| SCHEMBL31165961 | 0.93 | GRK5 (0.41) | GRK5METGRK2PIM1PIM2 | |
| SCHEMBL23012096 | 0.93 | GRK5 (0.41) | GRK5METGRK2PIM1PIM2 | |
| SCHEMBL28714674 | 0.88 | PIM1 (0.44) | METPIM1PIM2 | |
| SCHEMBL29479641 | 0.88 | PIM1 (0.44) | METPIM1PIM2 | |
| SCHEMBL29479792 | 0.86 | GRK5 (0.51) | GRK5METGRK2PIM1PIM2 | |
| SCHEMBL28713867 | 0.86 | GRK5 (0.51) | GRK5METGRK2PIM1PIM2 | |
| SCHEMBL24296549 | 0.86 | MAP3K5 (0.47) | RIPK1 | |
| SCHEMBL29479608 | 0.86 | ABL1 (0.41) | — | |
| SCHEMBL28713388 | 0.86 | ABL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |