Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK5 | P34947 | 6/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 16/20 | 0.47 |
| ▸ | GRK2 | P25098 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713867 | 1.00 | GRK5 (0.51) | GRK5PIM1PIM2METGRK2 | |
| SCHEMBL31165946 | 0.92 | GRK5 (0.46) | GRK5PIM1PIM2METGRK2 | |
| SCHEMBL29479765 | 0.86 | GRK5 (0.45) | GRK5PIM1PIM2METGRK2 | |
| SCHEMBL23012163 | 0.86 | GRK5 (0.45) | GRK5PIM1PIM2METGRK2 | |
| SCHEMBL23033561 | 0.86 | PIM1 (0.55) | PIM1PIM2MET | |
| SCHEMBL28714673 | 0.84 | GRK5 (0.49) | GRK5PIM1PIM2METGRK2 | |
| SCHEMBL29479735 | 0.83 | S1PR1 (0.41) | GRK5PIM1PIM2MET | |
| SCHEMBL28710692 | 0.83 | S1PR1 (0.41) | GRK5PIM1PIM2MET | |
| SCHEMBL28714669 | 0.82 | PIM1 (0.40) | PIM1PIM2 | |
| SCHEMBL28714630 | 0.81 | KDM4E (0.44) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |