Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 6/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479783 | 1.00 | AGPAT2 (0.55) | AGPAT2RXFP1MAPTTP53PTGS2 | |
| SCHEMBL28714635 | 0.89 | AGPAT2 (0.49) | AGPAT2RXFP1MAPTTP53KDM4E | |
| SCHEMBL23012208 | 0.88 | MAPT (0.60) | AGPAT2RXFP1MAPTTP53PTGS2 | |
| SCHEMBL23033327 | 0.83 | MAPT (0.53) | RXFP1MAPTTP53PTGS2KDM4E | |
| SCHEMBL23012342 | 0.80 | NPC1 (0.56) | AGPAT2RXFP1MAPTTP53PTGS2 | |
| Hydrochloric Acid SCHEMBL28714695 | 0.79 | MAPT (0.56) | AGPAT2RXFP1MAPTTP53KDM4E | |
| SCHEMBL28936032 | 0.78 | AGPAT2 (0.47) | AGPAT2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL30782723 | 0.76 | MAPT (0.66) | AGPAT2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL30782724 | 0.76 | MAPT (0.66) | AGPAT2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL23033340 | 0.76 | MAPT (0.53) | AGPAT2RXFP1MAPTTP53PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |