Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033325 | 0.91 | ALDH1A1 (0.51) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL23034143 | 0.86 | MAPT (0.71) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL29479624 | 0.86 | MAPT (0.53) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL23012893 | 0.86 | MAPT (0.53) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL29479738 | 0.85 | ALDH1A1 (0.64) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL31165939 | 0.84 | KDM4E (0.64) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL23012520 | 0.84 | KDM4E (0.64) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL23033340 | 0.83 | MAPT (0.53) | MAPTKDM4EPOLBALDH1A1NPSR1 | |
| SCHEMBL23033654 | 0.83 | MAPT (0.54) | MAPTKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL23012730 | 0.83 | AGPAT2 (0.55) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289826-A1 | SALT AND CRYSTAL FORM OF HA INHIBITOR COMPOUND | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-4282860-A1 | CRYSTAL FORM OF ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD FOR CRYSTAL FORM, AND USE OF CRYSTAL FORM | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022156737-A1 | CRYSTAL FORM OF ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD FOR CRYSTAL FORM, AND USE OF CRYSTAL FORM | 四川海思科制药有限公司 | 2022-07-28 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |