Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.74 |
| ▸ | MEN1 | O00255 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312917 | 0.85 | NPC1 (1.00) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12532252 | 0.84 | NPC1 (0.60) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12532277 | 0.80 | NPC1 (0.54) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12532296 | 0.80 | MEN1 (0.48) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL24989716 | 0.77 | MAPT (0.47) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL9665292 | 0.77 | MAPT (0.47) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7594159 | 0.77 | NPC1 (0.71) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16972797 | 0.77 | MAPT (0.50) | NPC1SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL1603455 | 0.77 | NPC1 (0.75) | NPC1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29702370 | 0.77 | MEN1 (0.74) | NPC1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2908843-B1 | TREATING CANCER | AGENCY SCIENCE TECH & RES (SG) | 2019-09-04 | — | — | EP | claimed |
| US-9889180-B2 | Method of treating cancer | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-13 | — | — | US | claimed |
| US-20150258175-A1 | METHOD OF TREATING CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-09-17 | — | — | US | claimed |
| EP-2908843-A1 | METHOD OF TREATING CANCER | Agency For Science, Technology And Research (SG) | 2015-08-26 | — | — | EP | claimed |
| WO-2014077784-A1 | METHOD OF TREATING CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-05-22 | — | — | WO | claimed |
| EP-2908843-B1 | TREATING CANCER | AGENCY SCIENCE TECH & RES (SG) | 2019-09-04 | — | — | EP | disclosed |
| US-9889180-B2 | Method of treating cancer | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-02-13 | — | — | US | disclosed |
| US-9874566-B2 | Compositions and methods for making and using oxygen sensing nanofibers and scaffolds | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-01-23 | — | — | US | disclosed |
| US-9874566-B2 | Compositions and methods for making and using oxygen sensing nanofibers and scaffolds | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160041177-A1 | COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS | Univ Virginia Patent Found (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160041177-A1 | COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS | Univ Virginia Patent Found (US) | 2016-02-11 | — | — | US | disclosed |
| US-20150258175-A1 | METHOD OF TREATING CANCER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-09-17 | — | — | US | disclosed |
| US-7955861-B2 | Luminescent diketonate polymers | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-06-07 | — | — | US | disclosed |
| WO-2011011646-A1 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100222420-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EZH2 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-09-02 | — | — | US | disclosed |
| US-20090137057-A1 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-05-28 | — | — | US | disclosed |
| US-20090137057-A1 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-05-28 | — | — | US | disclosed |
| US-20090012031-A1 | EZH2 Cancer Markers | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-01-08 | — | — | US | disclosed |
| WO-2009006577-A2 | COMPOSITIONS AND METHODS FOR INHIBITING EZH2 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-01-08 | — | — | WO | disclosed |
| WO-2007143209-A2 | LUMINESCENT DIKETONATE POLYMERS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160041177-A1 | COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS | ILK, HIF1A, TNNI3 | NPC1 4620/4885MEN1 3310/4885KMT2A 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.