SCHEMBL23014268

SCHEMBL23014268

CC1=Cc2c(cc3c(c2-c2cc(C)c(C)cc2C)CCC3)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CES1 P23141 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776064 1.00 MEN1 (0.34) MEN1KMT2ACES1MAPT
SCHEMBL27171022 0.86
SCHEMBL29853875 0.84 MEN1 (0.33) MEN1KMT2ACES1MAPT
SCHEMBL23014487 0.84 MEN1 (0.33) MEN1KMT2ACES1MAPT
SCHEMBL29882271 0.80 MEN1 (0.34) MEN1KMT2ACES1
SCHEMBL23014380 0.80 MEN1 (0.34) MEN1KMT2ACES1
Lithium SCHEMBL29882019 0.79 MEN1 (0.33) MEN1KMT2ACES1
SCHEMBL3697443 0.79 BRD4 (0.35) MEN1KMT2ACES1MAPT
SCHEMBL29596409 0.79 BRD4 (0.35) MEN1KMT2ACES1MAPT
SCHEMBL22777419 0.78 BRD4 (0.43) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4017887-A1 ISOTACTIC PROPYLENE HOMOPOLYMERS AND COPOLYMERS PRODUCED WITH C1 SYMMETRIC METALLOCENE CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2022-06-29 EP disclosed
WO-2021034459-A1 ISOTACTIC PROPYLENE HOMOPOLYMERS AND COPOLYMERS PRODUCED WITH C1 SYMMETRIC METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-25 WO disclosed