SCHEMBL3697443

SCHEMBL3697443

CC1=Cc2c(cc3c(c2-c2ccccc2)CCC3)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
KDM4E B2RXH2 4/20 0.34
MAPT P10636 4/20 0.34
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
MYC P01106 1/20 0.34
NLRP3 Q96P20 4/20 0.33
FPR1 P21462 1/20 0.33
ABCB1 P08183 1/20 0.32
MAPK1 P28482 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29596409 1.00 BRD4 (0.35) BRD4KDM4EMAPTHSD17B10ALDH1A1
SCHEMBL28723735 0.98 BRD4 (0.35) BRD4KDM4EMAPTHSD17B10ALDH1A1
Lithium SCHEMBL29767634 0.98 BRD4 (0.35) BRD4KDM4EMAPTHSD17B10ALDH1A1
SCHEMBL27171024 0.91 HSD17B10 (0.31) BRD4KDM4EMAPTHSD17B10ALDH1A1
SCHEMBL23014380 0.89 MEN1 (0.34) BRD4MEN1KMT2ANLRP3CES1
SCHEMBL29882271 0.89 MEN1 (0.34) BRD4MEN1KMT2ANLRP3CES1
Lithium SCHEMBL29882019 0.88 MEN1 (0.33) BRD4MEN1KMT2ANLRP3CES1
SCHEMBL22776383 0.85 FGF23 (0.32) KDM4EMEN1KMT2A
SCHEMBL29595700 0.85 FGF23 (0.32) KDM4EMEN1KMT2A
SCHEMBL23014487 0.84 MEN1 (0.33) MAPTALDH1A1MEN1KMT2ACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421334-B2 Hybrid supported metallocene catalyst and method of preparing polypropylene using the same LG CHEM, LTD. (KR) 2025-09-23 US disclosed
US-12358938-B2 Transition metal compound and method of preparing polypropylene using the same LG CHEM, LTD. (KR) 2025-07-15 US disclosed
US-12195563-B2 Polyolefin-based ionomers and production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-01-14 US disclosed
EP-3710491-B1 (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-01 EP disclosed
US-20240084056-A1 Polyolefin-Based Ionomers and Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-14 US disclosed
CN-116670188-A Polyolefin-based ionomers and preparation thereof 埃克森美孚化学专利公司 2023-08-29 CN disclosed
CN-113614119-B Hybrid supported metallocene catalyst and method for preparing polypropylene using the same 株式会社LG化学 2023-04-11 CN disclosed
US-20220213241-A1 Polyolefin-Based Ionomers and Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-07-07 US disclosed
CN-111372954-B Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight 埃克森美孚化学专利公司 2022-06-28 CN disclosed
US-20220144983-A1 HYBRID SUPPORTED METALLOCENE CATALYST AND METHOD OF PREPARING POLYPROPYLENE USING THE SAME LG CHEM, LTD. (KR) 2022-05-12 US disclosed
WO-2020251265-A1 HYBRID SUPPORTED METALLOCENE CATALYST, AND METHOD FOR PREPARING POLYPROPYLENE USING SAME 주식회사 엘지화학 2020-12-17 WO disclosed
WO-2020251247-A1 NOVEL TRANSITION METAL COMPOUND AND METHOD FOR PREPARING POLYPROPYLENE USING SAME 주식회사 엘지화학 2020-12-17 WO disclosed
EP-3710491-A1 (DI)SILICON BRIDGED METALLOCENES THAT PRODUCE POLYETHYLENE BROAD MOLECULAR WEIGHT DISTRIBUTION AND MOLECULAR WEIGHT ExxonMobil Chemical Patents Inc. (US) 2020-09-23 EP disclosed
CN-111372954-A Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight 埃克森美孚化学专利公司 2020-07-03 CN disclosed
US-20190144571-A1 (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight EXXONMOBIL CHEMICAL PATENTS INC. 2019-05-16 US disclosed
EP-1692144-B1 ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2010-04-14 EP disclosed
US-7452949-B2 Organometallic transition metal compound, biscyclopentadienyl ligand system, catalyst system and preparation of polyolefins BASELL POLYOLEFINE GMBH (DE) 2008-11-18 US disclosed
US-20070155919-A1 Organometallic transition metal compound, biscyclopentadienyl ligand system, catalyst system and preparation of polyolefins BASELL POLYOLEFINE GMBH (DE) 2007-07-05 US disclosed
EP-1692144-A2 ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS Basell Polyolefine GmbH (DE) 2006-08-23 EP disclosed
WO-2005058916-A2 ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PREPARATION OF POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155919-A1 Organometallic transition metal compound, biscyclopentadienyl ligand system, catalyst system and preparation of polyolefins SOD1, ORC3, OPRM1 BRD4 1648/4885KDM4E 3691/4885MAPT 3726/4885
US-12358938-B2 Transition metal compound and method of preparing polypropylene using the same PMS2, MUS81, PMM2 BRD4 3640/4885KDM4E 3312/4885MAPT 1260/4885
US-20190144571-A1 (Di)Silicon Bridged Metallocenes that Produce Polyethylene with Broad Molecular Weight Distribution and High Molecular Weight MDM4, MAL2, MSI2 BRD4 264/4885KDM4E 1400/4885MAPT 3244/4885
US-20220144983-A1 HYBRID SUPPORTED METALLOCENE CATALYST AND METHOD OF PREPARING POLYPROPYLENE USING THE SAME PMS2, POP1, POLA1 BRD4 3699/4885KDM4E 4344/4885MAPT 2016/4885
US-12421334-B2 Hybrid supported metallocene catalyst and method of preparing polypropylene using the same PMS2, POP1, POLA1 BRD4 3699/4885KDM4E 4344/4885MAPT 2016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.