Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.62 |
| ▸ | CYCS | P99999 | 4/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664820 | 0.97 | TOP1 (0.66) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL8909228 | 0.80 | GRIN2D (0.53) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL7672026 | 0.79 | TOP1 (0.59) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL21703115 | 0.78 | TOP1 (0.81) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL29354037 | 0.77 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL709532 | 0.77 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL30925005 | 0.77 | TOP1 (0.57) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL2240990 | 0.76 | TOP1 (0.60) | TOP1CYCSENPP2TERT | |
| SCHEMBL3794157 | 0.76 | TOP1 (0.61) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL1497141 | 0.76 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11629160-B2 | Corrole-based frameworks and methods of use thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-04-18 | — | — | US | disclosed |
| US-20220267361-A1 | CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF | UNIVERSITY OF SOUTH FLORIDA | 2022-08-25 | — | — | US | disclosed |
| WO-2021035010-A1 | CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF | MA SHENGQIAN (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629160-B2 | Corrole-based frameworks and methods of use thereof | CA13, CA12, ERCC4 | TOP1 1379/4885CYCS 67/4885ENPP2 3724/4885 |
| US-20220267361-A1 | CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF | CA13, CA12, ERCC4 | TOP1 1379/4885CYCS 67/4885ENPP2 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.