SCHEMBL2240990

SCHEMBL2240990

C1=Cc2nc1c(-c1ccccc1)c1ccc([nH]1)c(-c1ccccc1)c1ccc([nH]1)c(-c1ccccc1)c1ccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.60
▸ STAT3 P40763 1/20 0.59
▸ STAT1 P42224 1/20 0.59
▸ CYCS P99999 3/20 0.58
▸ TERT O14746 4/20 0.57
▸ ENPP2 Q13822 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30136 0.96 TOP1 (0.64) TOP1STAT3STAT1CYCSTERT
SCHEMBL29405434 0.96 TOP1 (0.64) TOP1STAT3STAT1CYCSTERT
SCHEMBL7987113 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL9640434 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL483081 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL8014529 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL15085674 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL1313700 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL8014524 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT
SCHEMBL991489 0.94 TOP1 (0.62) TOP1STAT3STAT1CYCSTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) 2026-02-19 — — US claimed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 — — US claimed
US-20220267361-A1 CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF UNIVERSITY OF SOUTH FLORIDA 2022-08-25 — — US claimed
US-20210292353-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-09-23 — — US claimed
EP-3829565-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2021-06-09 — — EP claimed
WO-2021035010-A1 CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF MA SHENGQIAN (US) 2021-02-25 — — WO claimed
WO-2020025488-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2020-02-06 — — WO claimed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 — — US claimed
US-8480928-B2 Inorganic-organic composite luminophore KARLSRUHER INSTITUT FUR TECHNOLOGIE (KIT) (DE) 2013-07-09 — — US claimed
US-20110198538-A1 INORGANIC-ORGANIC COMPOSITE LUMINOPHORE Karlsruher Institut for Technologie (KIT) (DE) 2011-08-18 — — US claimed
EP-2179006-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE Karlsruher Institut für Technologie (DE) 2010-04-28 — — EP claimed
WO-2009100800-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE UNIVERSITÄT KARLSRUHE (TH) (DE) 2009-08-20 — — WO claimed
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) 2026-02-19 — — US disclosed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 — — US disclosed
US-11629160-B2 Corrole-based frameworks and methods of use thereof UNIVERSITY OF SOUTH FLORIDA (US) 2023-04-18 — — US disclosed
US-20220267361-A1 CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF UNIVERSITY OF SOUTH FLORIDA 2022-08-25 — — US disclosed
WO-2015043533-A1 PHOTOVOLTAIC CONVERSION ELEMENT AND PHOTOVOLTAIC CELL THE UNIVERSITY OF HONG KONG (CN) 2015-04-02 — — WO disclosed
US-20150090337-A1 PHOTOVOLTAIC CONVERSION ELEMENT AND PHOTOVOLTAIC CELL THE UNIVERSITY OF HONG KONG (HK) 2015-04-02 — — US disclosed
EP-2179006-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE Karlsruher Institut für Technologie (DE) 2010-04-28 — — EP disclosed
WO-2009100800-A1 INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE UNIVERSITÄT KARLSRUHE (TH) (DE) 2009-08-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048152-A1 GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES GOT1, RNMT, GNAO1 TOP1 261/4885STAT3 1715/4885STAT1 994/4885
US-11629160-B2 Corrole-based frameworks and methods of use thereof CA13, CA12, ERCC4 TOP1 1379/4885STAT3 2245/4885STAT1 2505/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 TOP1 3915/4885STAT3 2646/4885STAT1 4147/4885
US-20220267361-A1 CORROLE-BASED FRAMEWORKS AND METHODS OF USE THEREOF CA13, CA12, ERCC4 TOP1 1379/4885STAT3 2245/4885STAT1 2505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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