SCHEMBL23015186

SCHEMBL23015186

CCOCCCCCCCCCCCCC#CC1CCCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23014792 0.98 KDM4E (0.31) EPHX2
SCHEMBL23014939 0.96 EPHX2 (0.31) EPHX2ALDH1A1TDP1
SCHEMBL23014717 0.93 EPHX2 (0.32) EPHX2ALDH1A1TDP1
SCHEMBL23014725 0.88 SPHK2 (0.34) EPHX2ALDH1A1TDP1
SCHEMBL23014920 0.86 SPHK2 (0.33) EPHX2ALDH1A1TDP1
SCHEMBL23015193 0.84 SPHK2 (0.34) EPHX2ALDH1A1TDP1
SCHEMBL23014713 0.80 SPHK2 (0.36) EPHX2ALDH1A1TDP1
SCHEMBL23014865 0.74
SCHEMBL19317543 0.73 HCAR2 (0.34)
SCHEMBL23034226 0.72 PTPN7 (0.41) EPHX2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220298185-A1 Nucleoside Prodrugs and Uses Related Thereto UNIV EMORY (US) 2022-09-22 US claimed
EP-4017499-A1 NUCLEOSIDE PRODRUGS AND USES RELATED THERETO Emory University (US) 2022-06-29 EP claimed
WO-2021035214-A1 NUCLEOSIDE PRODRUGS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2021-02-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298185-A1 Nucleoside Prodrugs and Uses Related Thereto PNPO, GSTO1, CYP2C18 EPHX2 172/4885ALDH1A1 735/4885TDP1 1205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.