⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765190 | 0.64 | — | — | |
| SCHEMBL1015818 | 0.56 | — | — | |
| SCHEMBL17081022 | 0.55 | — | — | |
| SCHEMBL24931210 | 0.54 | — | — | |
| SCHEMBL5138535 | 0.51 | — | — | |
| SCHEMBL23471309 | 0.51 | — | — | |
| SCHEMBL17541720 | 0.51 | — | — | |
| SCHEMBL4999739 | 0.49 | — | — | |
| SCHEMBL7018754 | 0.49 | — | — | |
| SCHEMBL762235 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10925874-B2 | Substituted pyrazolopyrimidines as glucocerebrosidase activators | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-02-23 | — | — | US | disclosed |