⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831046 | 0.67 | — | — | |
| SCHEMBL17527409 | 0.66 | — | — | |
| SCHEMBL6994558 | 0.57 | — | — | |
| SCHEMBL2994409 | 0.57 | — | — | |
| SCHEMBL12520990 | 0.56 | — | — | |
| SCHEMBL7018754 | 0.55 | — | — | |
| SCHEMBL8523235 | 0.55 | — | — | |
| SCHEMBL762235 | 0.54 | — | — | |
| SCHEMBL1127083 | 0.54 | — | — | |
| SCHEMBL23330241 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434400-B2 | Assembly components comprising curable compositions containing acetoacetylated resins | EASTMAN CHEMICAL COMPANY (US) | 2022-09-06 | — | — | US | disclosed |
| US-20210130473-A1 | TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2021-05-06 | — | — | US | disclosed |
| US-7414045-B2 | Substituted pyrimido[1,2-a]azepines useful as HIV integrase inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2008-08-19 | — | — | US | disclosed |
| US-4588526-A | Bronchodilatory azepino(1,2-A)pyrimidine derivatives and acid addition salts thereof and bronchodilating pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-05-13 | — | — | US | disclosed |
| US-4588526-A | Bronchodilatory azepino(1,2-A)pyrimidine derivatives and acid addition salts thereof and bronchodilating pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-05-13 | — | — | US | disclosed |
| US-4588526-A | Bronchodilatory azepino(1,2-A)pyrimidine derivatives and acid addition salts thereof and bronchodilating pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-05-13 | — | — | US | disclosed |
| EP-0000392-B1 | CEPHALOSPORINS AND PENICILLINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |