Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068747 | 0.87 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL20068748 | 0.86 | DYRK1A (1.00) | DYRK1A | |
| Hydrochloric Acid SCHEMBL30417034 | 0.85 | DYRK1A (0.98) | DYRK1A | |
| Hydrochloric Acid SCHEMBL29159571 | 0.85 | DYRK1A (0.98) | DYRK1A | |
| SCHEMBL23015693 | 0.83 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL30417087 | 0.83 | DYRK1A (1.00) | DYRK1A | |
| SCHEMBL23015753 | 0.83 | DYRK1A (0.71) | DYRK1A | |
| SCHEMBL30416842 | 0.83 | DYRK1A (0.71) | DYRK1A | |
| SCHEMBL23015687 | 0.83 | DYRK1A (0.79) | DYRK1A | |
| SCHEMBL30833187 | 0.83 | DYRK1A (0.79) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | PHARMASUM THERAPEUTICS AS (NO) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | DYRK1A, DYRK1B, PDK2 | DYRK1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.