SCHEMBL30833187

SCHEMBL30833187

COc1ccc2sc(-c3cnccc3NC(=O)CNC(=O)OC(C)(C)C)nc2c1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23015687 1.00 DYRK1A (0.79) DYRK1A
SCHEMBL23015688 0.90 DYRK1A (0.76) DYRK1A
SCHEMBL30833188 0.90 DYRK1A (0.76) DYRK1A
SCHEMBL20068747 0.88 DYRK1A (1.00) DYRK1A
SCHEMBL20068748 0.84 DYRK1A (1.00) DYRK1A
SCHEMBL23015689 0.83 DYRK1A (1.00) DYRK1A
Hydrochloric Acid SCHEMBL29159571 0.83 DYRK1A (0.98) DYRK1A
Hydrochloric Acid SCHEMBL30417034 0.83 DYRK1A (0.98) DYRK1A
SCHEMBL20069005 0.82 DYRK1A (0.72) DYRK1A
SCHEMBL23015693 0.81 DYRK1A (1.00) DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3526216-B1 BENZOTHIAZOLE DERIVATIVES AS DYRK1 INHIBITORS PHARMASUM THERAPEUTICS AS (NO) 2024-04-03 EP disclosed