Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12176731 | 1.00 | POLB (0.47) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL14659855 | 0.98 | POLB (0.46) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL14659854 | 0.98 | POLB (0.46) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL15304225 | 0.90 | POLB (0.42) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL15304224 | 0.90 | POLB (0.42) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL15304223 | 0.90 | POLB (0.42) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL15304226 | 0.90 | POLB (0.42) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL22572268 | 0.83 | CHRNB2 (0.48) | POLBSMN1; SMN2TP53ALDH1A1GAA | |
| SCHEMBL12176737 | 0.82 | MAPT (0.51) | POLBALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL24454487 | 0.81 | POLB (0.45) | POLBSMN1; SMN2TP53ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018150-A1 | SMALL MOLECULAR INHIBITOR AGAINST BTK AND/OR BTK C481S AND USE THEREOF | ARROMAX PHARMATECH CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | PHARMASUM THERAPEUTICS AS (NO) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | DYRK1A, DYRK1B, PDK2 | POLB 2360/4885SMN1; SMN2 2813/4885TP53 731/4885 |
| US-20240018150-A1 | SMALL MOLECULAR INHIBITOR AGAINST BTK AND/OR BTK C481S AND USE THEREOF | BTK, SYK, LCK | POLB 2758/4885SMN1; SMN2 4759/4885TP53 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.