Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627388 | 0.87 | PRKCI (0.63) | KDM4ELMNACYP3A4TSHRPRKCI | |
| SCHEMBL21982078 | 0.76 | KDM4E (0.50) | KDM4ELMNACYP3A4TSHRPRKCI | |
| SCHEMBL4863259 | 0.76 | S1PR1 (0.48) | PRKCIMAPTHSD17B10ALDH1A1NR3C2 | |
| SCHEMBL17873933 | 0.76 | KDM4E (0.73) | KDM4ELMNACYP3A4TSHRHSD17B10 | |
| SCHEMBL6079794 | 0.75 | MEN1 (0.41) | KDM4EPRKCIMAPTHSD17B10ALDH1A1 | |
| SCHEMBL15880595 | 0.75 | SMARCA2 (0.61) | MAPTHSD17B10NR3C2 | |
| SCHEMBL15880501 | 0.73 | PRKCI (0.62) | LMNAPRKCIARCYP1A2POLB | |
| SCHEMBL23015740 | 0.73 | SREBF2 (0.57) | KDM4ELMNACYP3A4TSHRMAPT | |
| SCHEMBL2998832 | 0.73 | KDM4E (0.64) | KDM4ELMNACYP3A4TSHRPRKCI | |
| SCHEMBL4701803 | 0.73 | NR3C2 (0.55) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | PHARMASUM THERAPEUTICS AS (NO) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927106-B2 | Benzothiazole derivatives as DYRK1 inhibitors | DYRK1A, DYRK1B, PDK2 | KDM4E 984/4885LMNA 4785/4885CYP3A4 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.