Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168491 | 0.85 | TAAR1 (0.70) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL30147114 | 0.85 | TAAR1 (0.70) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8515123 | 0.85 | SLC6A4 (0.74) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4168488 | 0.85 | TAAR1 (0.70) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4170645 | 0.85 | TAAR1 (0.70) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| Safrolglycol SCHEMBL11447270 | 0.84 | CYP3A4 (1.00) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| Safrolglycol SCHEMBL29368350 | 0.84 | CYP3A4 (1.00) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| Safrolglycol SCHEMBL7510518 | 0.84 | CYP3A4 (1.00) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25190612 | 0.82 | CYP3A4 (0.73) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19342841 | 0.82 | TAAR1 (0.66) | CYP3A4TAAR1SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927124-B2 | Compounds and compositions and uses thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927124-B2 | Compounds and compositions and uses thereof | CHAT, ACHE, MAOB | CYP3A4 580/4885TAAR1 893/4885SLC6A4 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.