Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 3/20 | 0.57 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.57 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.57 |
| ▸ | GJB2 | P29033 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 2/20 | 0.40 |
| ▸ | SELP | P16109 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625445 | 0.86 | MAPK1 (0.52) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL4320956 | 0.86 | MAPK1 (0.52) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL25005885 | 0.86 | LGALS8 (0.57) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22067762 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22067763 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL21068067 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL23393554 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL25005884 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL22431206 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 | |
| SCHEMBL23183598 | 0.85 | LGALS8 (0.77) | LGALS8LGALS3LGALS4GJB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |