Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 20/20 | 0.79 |
| ▸ | THRA | P10827 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sobetirome SCHEMBL29467327 | 0.88 | THRB (1.00) | THRBTHRA | |
| Sobetirome SCHEMBL282119 | 0.88 | THRB (1.00) | THRBTHRA | |
| SCHEMBL12642742 | 0.84 | THRB (0.75) | THRBTHRA | |
| SCHEMBL282795 | 0.84 | THRB (1.00) | THRBTHRA | |
| SCHEMBL22095710 | 0.84 | THRB (0.91) | THRBTHRA | |
| SCHEMBL19655550 | 0.83 | THRB (0.82) | THRBTHRA | |
| SCHEMBL3160844 | 0.83 | THRB (0.71) | THRBTHRA | |
| SCHEMBL19920595 | 0.82 | THRB (0.72) | THRBTHRA | |
| SCHEMBL19859395 | 0.82 | THRB (0.80) | THRBTHRA | |
| SCHEMBL18028276 | 0.82 | THRB (0.72) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237605-B1 | IMPROVEMENTS IN OLIGODENDROGLIAL CELL CULTURING METHODS AND IN METHODS FOR TREATING NEURODEGENERATIVE DISORDERS BY USING THYROID HORMONES OR ANALOGUES | NEUORPHAN PTY LTD (AU) | 2021-02-24 | — | — | EP | disclosed |