SCHEMBL23018367

SCHEMBL23018367

Cc1cccc(N)c1/C=C\N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.48
CYP3A4 P08684 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 3/20 0.42
PIK3CA P42336 1/20 0.42
ALDH1A1 P00352 3/20 0.35
DPP4 P27487 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16130441 0.86 CYP2A6 (0.39) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL12825541 0.83 CD44 (0.48) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL24180294 0.81 CD44 (0.46) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL19121820 0.78 CD44 (0.43) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL13947724 0.78 CD44 (0.43) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL3363239 0.76 CD44 (0.50) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL12666967 0.76 CD44 (0.50) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL18967032 0.76 CD44 (0.50) CD44CYP3A4TDP1TSHRPIK3CA
SCHEMBL10079313 0.74 ALDH1A1 (0.33) CD44TDP1TSHRALDH1A1CYP1A2
SCHEMBL20125056 0.74 TAAR1 (0.39) CD44DPP4CYP1A2CYP2A6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556750-B1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING SAME LG CHEMICAL LTD (KR) 2021-02-24 EP disclosed