Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667317 | 0.84 | SMN1; SMN2 (0.52) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL10272312 | 0.82 | SMN1; SMN2 (0.56) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL23018554 | 0.82 | TDP1 (0.37) | GAASMN1; SMN2LMNAALDH1A1TDP1 | |
| SCHEMBL21229101 | 0.80 | GAA (0.51) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL30212327 | 0.79 | SMN1; SMN2 (0.56) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL27596595 | 0.79 | SMN1; SMN2 (0.56) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL18291769 | 0.79 | SMN1; SMN2 (0.56) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL3131672 | 0.79 | SMN1; SMN2 (0.56) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL12157023 | 0.78 | SMN1; SMN2 (0.52) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL18641410 | 0.78 | SMN1; SMN2 (0.55) | GAASMN1; SMN2LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |