Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018564 | 0.82 | GAA (0.52) | TDP1SMN1; SMN2GAAALDH1A1OGA | |
| SCHEMBL21229095 | 0.82 | GAA (0.36) | SMN1; SMN2GAAALDH1A1HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL18641370 | 0.79 | OGA (0.46) | TDP1SMN1; SMN2GAAALDH1A1OGA | |
| SCHEMBL18667145 | 0.78 | L3MBTL1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18641375 | 0.72 | HRH3 (0.36) | SMN1; SMN2GAAALDH1A1OGAHRH3 | |
| SCHEMBL18667148 | 0.70 | EIF2AK4 (0.35) | SMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL17541603 | 0.69 | OGA (0.78) | OGA | |
| SCHEMBL21229034 | 0.68 | TDP1 (0.50) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3071381 | 0.68 | LMNA (0.43) | TDP1ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL18667317 | 0.67 | SMN1; SMN2 (0.52) | TDP1SMN1; SMN2GAAALDH1A1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |