Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293759 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL27900437 | 0.84 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2D6NPSR1KMT2A | |
| SCHEMBL9601863 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL10615621 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6KMT2ACES2 | |
| SCHEMBL11600373 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL9771995 | 0.81 | CYP1A2 (0.67) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL28832590 | 0.80 | MEN1 (0.45) | ALDH1A1CYP1A2SMN1; SMN2KMT2ACYP3A4 | |
| SCHEMBL13168067 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL31173896 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL13034095 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2D6PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954815-B1 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI INC (US) | 2015-02-25 | — | — | EP | disclosed |
| US-8795984-B2 | Production of glycoproteins with reduced O-glycosylation | MERCK SHARP & DOHME CORP. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8501438-B2 | Production of glycoproteins with reduced O-glycosylation | GLYCOFI, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| CN-101365783-B | Production of glycoproteins with reduced o-glycosylation | GLYCOFI INC | 2013-07-17 | — | — | CN | disclosed |
| US-8461183-B2 | PPAR agonist compounds, preparation and uses | GENFIT (FR) | 2013-06-11 | — | — | US | disclosed |
| US-20120322101-A1 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC. (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120237973-A1 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8206949-B2 | Production of glycoproteins with reduced O-glycosylation | GLYCOFI, INC. (US) | 2012-06-26 | — | — | US | disclosed |
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | GENFIT (FR) | 2011-08-11 | — | — | US | disclosed |
| US-20090170159-A1 | PRODUCTION OF GLYCOPROTEINS WITH REDUCED O-GLYCOSYLATION | GLYCOFI, INC (US) | 2009-07-02 | — | — | US | disclosed |
| US-20060079696-A1 | Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses | GENFIT (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-01-08 | — | — | US | disclosed |
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |
| EP-0823896-B1 | SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS | SCHERING CORP (US) | 2001-07-11 | — | — | EP | disclosed |
| US-5840725-A | Substituted oximes, hydrazones and olefins as neurokinin antagonists | SCHERING CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0823896-A1 | SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1998-02-18 | — | — | EP | disclosed |
| US-5696267-A | ANTIHISTAMINES; ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS | SCHERING CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1996034857-A1 | SUBSTITUTED OXIMES, HYDRAZONES AND OLEFINS AS NEUROKININ ANTAGONISTS | SCHERING CORPORATION (US) | 1996-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | PPARD, PPARA, PPARG | ALDH1A1 1483/4885CYP1A2 918/4885CYP2D6 1738/4885 |
| US-20060079696-A1 | Substituted compounds derived from N-(benzyl)phenylacetamide, preparation and uses | AADAC, NAT1, PARN | ALDH1A1 845/4885CYP1A2 133/4885CYP2D6 450/4885 |
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | SLC5A2, OXSR1, SLC5A1 | ALDH1A1 2757/4885CYP1A2 1193/4885CYP2D6 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.