Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15901746 | 0.87 | SCN8A (0.65) | JAK2JAK1TYK2SCN8ASCN10A | |
| SCHEMBL15902019 | 0.84 | SCN8A (0.67) | JAK2JAK1TYK2SCN8ASCN10A | |
| SCHEMBL23027346 | 0.80 | SCN8A (0.61) | SCN8ASCN10A | |
| SCHEMBL22203108 | 0.80 | BRAF (0.42) | JAK2JAK1 | |
| SCHEMBL29398470 | 0.80 | BRAF (0.42) | JAK2JAK1 | |
| SCHEMBL30065545 | 0.80 | SCN8A (0.53) | SCN8ASCN10A | |
| SCHEMBL28654766 | 0.80 | SCN8A (0.53) | SCN8ASCN10A | |
| SCHEMBL15902052 | 0.80 | SCN8A (0.69) | JAK2JAK1TYK2SCN8ASCN10A | |
| SCHEMBL15901646 | 0.79 | SCN10A (0.72) | SCN8ASCN10A | |
| SCHEMBL15901652 | 0.79 | SCN10A (0.69) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032074-A1 | BENZAMIDE FUSED AROMATIC RING DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-02-25 | — | — | WO | disclosed |