SCHEMBL23027751

SCHEMBL23027751

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NC(C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.65
ALDH1A1 P00352 4/20 0.63
MEN1 O00255 3/20 0.63
FAAH O00519 3/20 0.63
BLM P54132 3/20 0.63
KMT2A Q03164 3/20 0.63
MAPT P10636 3/20 0.63
HPGD P15428 3/20 0.63
TDP1 Q9NUW8 3/20 0.63
KDM4E B2RXH2 2/20 0.63
USP2 O75604 2/20 0.63
CYP3A4 P08684 2/20 0.63
ALOX15 P16050 2/20 0.63
RECQL P46063 2/20 0.63
HSD17B10 Q99714 2/20 0.63
POLB P06746 1/20 0.63
APEX1 P27695 1/20 0.63
PMP22 Q01453 1/20 0.63
GPR18 Q14330 1/20 0.63
SLC6A5 Q9Y345 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22461508 0.95 HRH3 (0.66) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL11260057 0.90 HRH3 (0.71) MEN1FAAHBLMKMT2AMAPT
SCHEMBL11260061 0.90 HRH3 (0.71) MEN1FAAHBLMKMT2AMAPT
Bromide SCHEMBL2169637 0.89 HRH3 (0.69) MEN1FAAHBLMKMT2AMAPT
SCHEMBL28340381 0.88 HRH3 (0.59) MEN1FAAHBLMKMT2AMAPT
SCHEMBL3233808 0.86 MEN1 (0.62) CNR1ALDH1A1MEN1FAAHBLM
SCHEMBL3233804 0.86 MEN1 (0.62) CNR1ALDH1A1MEN1FAAHBLM
SCHEMBL11731139 0.84 HRH3 (0.64) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL27447674 0.82 HRH3 (0.69) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL16626967 0.82 MEN1 (0.63) CNR1ALDH1A1MEN1BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168428-A1 CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS GRAPHIUM BIOSCIENCES, INC. (US) 2022-06-02 US disclosed
US-20210052631-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE IONIS PHARMACEUTICALS, INC. (US) 2021-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168428-A1 CANNABINOID GLYCOSIDE PRODRUGS AND METHODS OF SYNTHESIS CNR2, CNR1, UGCG CNR1 2/4885ALDH1A1 1324/4885MEN1 3588/4885
US-20210052631-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE SNRPE, FABP1, RNASE1 CNR1 4605/4885ALDH1A1 3720/4885MEN1 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.