⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24842107 | 1.00 | — | — | |
| SCHEMBL25769684 | 0.77 | EPHX2 (0.34) | — | |
| SCHEMBL25769682 | 0.77 | EPHX2 (0.34) | — | |
| SCHEMBL21618647 | 0.77 | ANPEP (0.32) | — | |
| SCHEMBL23029496 | 0.77 | ANPEP (0.32) | — | |
| SCHEMBL25994335 | 0.77 | SAT1 (0.38) | — | |
| SCHEMBL24842354 | 0.77 | EPHX2 (0.34) | — | |
| SCHEMBL24129485 | 0.77 | SAT1 (0.38) | — | |
| SCHEMBL24842118 | 0.75 | ANPEP (0.31) | — | |
| SCHEMBL22151776 | 0.75 | HTR2C (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212155-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20230212155-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20210053946-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2021-02-25 | — | — | US | disclosed |