Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24129485 | 1.00 | SAT1 (0.38) | SAT1TP53 | |
| SCHEMBL26050306 | 0.83 | SAT1 (0.35) | SAT1 | |
| SCHEMBL4224771 | 0.80 | SAT1 (0.50) | SAT1 | |
| SCHEMBL23482088 | 0.80 | — | — | |
| SCHEMBL4224780 | 0.80 | SAT1 (0.50) | SAT1 | |
| SCHEMBL24842107 | 0.77 | — | — | |
| SCHEMBL23029495 | 0.77 | — | — | |
| SCHEMBL17113716 | 0.76 | — | — | |
| SCHEMBL10034558 | 0.74 | — | — | |
| SCHEMBL17778091 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820573-B1 | 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES | NOVARTIS AG (CH) | 2023-08-09 | — | — | EP | disclosed |