Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301002 | 0.90 | P2RY12 (0.50) | P2RY12RAB9AL3MBTL1KMT2AMAPT | |
| SCHEMBL3310147 | 0.89 | P2RY12 (0.49) | P2RY12RAB9AL3MBTL1KMT2AMEN1 | |
| SCHEMBL3308028 | 0.84 | P2RY12 (0.51) | P2RY12RAB9AL3MBTL1KMT2AMAPT | |
| SCHEMBL2357597 | 0.84 | KDM4E (0.49) | P2RY12RAB9AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL3311413 | 0.83 | USP30 (0.53) | P2RY12RAB9AL3MBTL1KMT2AMAPT | |
| SCHEMBL13363955 | 0.82 | KCNQ3 (0.57) | RAB9AL3MBTL1MAPTCYP1A2CYP2C19 | |
| SCHEMBL2305153 | 0.82 | RAB9A (0.49) | RAB9AL3MBTL1MAPTCYP1A2CYP2C19 | |
| SCHEMBL2300887 | 0.81 | RAB9A (0.47) | P2RY12RAB9AL3MBTL1MAPTCYP1A2 | |
| SCHEMBL2357220 | 0.81 | RAB9A (0.45) | P2RY12RAB9AL3MBTL1KMT2AMEN1 | |
| SCHEMBL2356882 | 0.81 | RAB9A (0.50) | RAB9AL3MBTL1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350311-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010056506-A1 | DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |