3-Methylbutanoic Acid

3-Methylbutanoic Acid

SCHEMBL2303256

CC(C)CC(=O)O.CCCC

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CACNA2D1 P54289 2/20 0.44
CACNB3 P54284 1/20 0.44
CACNA1C Q13936 1/20 0.44
PGR P06401 1/20 0.44
ADRA1A P35348 1/20 0.44
HTR2B P41595 1/20 0.44
CACNA2D2 Q9NY47 1/20 0.44
CA2 P00918 1/20 0.43
GPR84 Q9NQS5 4/20 0.43
FFAR3 O14843 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methylbutanoic Acid SCHEMBL1331498 0.91
3-Methylbutanoic Acid SCHEMBL467274 0.91 TDP1 (0.56) TDP1ALDH1A1CACNA2D1CACNB3CACNA1C
3-Methylbutanoic Acid SCHEMBL43436 0.91
3-Methylbutanoic Acid SCHEMBL627178 0.89 GPR84 (0.56) TDP1ALDH1A1GPR84SLC22A6
3-Methylbutanoic Acid SCHEMBL1373554 0.88 TDP1 (0.48) TDP1ALDH1A1CACNA2D1CACNB3CACNA1C
3-Methylbutanoic Acid SCHEMBL5511012 0.88 FFAR3 (0.59) TDP1ALDH1A1CACNA2D1CACNB3CACNA1C
3-Methylbutanoic Acid SCHEMBL6139482 0.88
3-Methylbutanoic Acid SCHEMBL6113289 0.88
3-Methylbutanoic Acid SCHEMBL9185998 0.88
3-Methylbutanoic Acid SCHEMBL15772049 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106602013-B Preparation method of sulfur-activated carbon/graphene composite material 中国科学院山西煤炭化学研究所 2020-11-27 CN disclosed
US-8834865-B2 Delivery system for co-formulated enzyme and substrate DANISCO US INC. (US) 2014-09-16 US disclosed
EP-2350250-B1 DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE DANISCO US INC (US) 2014-02-19 EP disclosed
EP-2350250-A1 DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE Danisco US Inc. (US) 2011-08-03 EP disclosed
WO-2010062745-A1 DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE DANISCO US INC. (US) 2010-06-03 WO disclosed