SCHEMBL23033334

SCHEMBL23033334

CCC1(CN)CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 1/20 0.40
EPHX2 P34913 1/20 0.40
OPRD1 P41143 1/20 0.39
OPRK1 P41145 1/20 0.39
RECQL P46063 1/20 0.38
EPHX1 P07099 1/20 0.38
DPP4 P27487 1/20 0.38
NR1H2 P55055 1/20 0.38
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
ATM Q13315 1/20 0.37
TACR1 P25103 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18418212 0.92 USP2 (0.50) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL18309957 0.91 USP2 (0.41) USP2SMN1; SMN2HPGDOPRD1OPRK1
SCHEMBL25630169 0.90 USP2 (0.51) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL346018 0.88 USP2 (0.44) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL16565814 0.88 USP2 (0.46) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL12884306 0.86 USP2 (0.47) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL3963649 0.85 USP2 (0.42) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL21148250 0.84 USP2 (0.46) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL20868676 0.83 SMN1; SMN2 (0.40) USP2SMN1; SMN2HPGDEPHX2OPRD1
SCHEMBL12598227 0.83 GPR119 (0.41) USP2SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991706-A PIM kinase inhibitors 杭州邦顺制药有限公司 2023-04-21 CN disclosed
WO-2021032209-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 2021-02-25 WO disclosed