Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.42 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033529 | 0.86 | ALDH1A1 (0.49) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL28713841 | 0.85 | NPC1 (0.42) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033300 | 0.84 | MAPT (0.44) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033441 | 0.84 | KDM4E (0.44) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23034036 | 0.83 | NPC1 (0.40) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033444 | 0.83 | KDM4E (0.42) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033436 | 0.83 | KDM4E (0.42) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033446 | 0.83 | KDM4E (0.42) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23034046 | 0.80 | ALDH1A1 (0.45) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL23033732 | 0.80 | ALDH1A1 (0.48) | NPC1RAB9AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |