Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297401 | 1.00 | ACHE (0.39) | ACHEBACE1RXFP1ATRSYK | |
| SCHEMBL20577759 | 0.78 | RXFP1 (0.44) | ACHEBACE1RXFP1ATRSYK | |
| SCHEMBL16992929 | 0.75 | ATR (0.44) | RXFP1ATRNAMPTCYP17A1 | |
| SCHEMBL12871048 | 0.72 | HDAC1 (0.43) | RXFP1NAMPTHDAC1CYP17A1 | |
| SCHEMBL13345491 | 0.71 | SMN1; SMN2 (0.47) | ACHEBACE1RXFP1HDAC1CA12 | |
| SCHEMBL6096909 | 0.71 | CA1 (0.48) | ACHEBACE1NAMPTSNCAHDAC1 | |
| SCHEMBL1136944 | 0.71 | CA12 (0.48) | ACHEBACE1RXFP1SYKNAMPT | |
| SCHEMBL31606978 | 0.71 | CA12 (0.48) | ACHEBACE1RXFP1SYKNAMPT | |
| SCHEMBL2596875 | 0.70 | AR (0.56) | ATRSYKNAMPTHDAC1CYP17A1 | |
| SCHEMBL14980804 | 0.70 | CYP17A1 (0.43) | ACHEBACE1RXFP1NAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |