SCHEMBL2303374

SCHEMBL2303374

O=C(O)C=Cc1cccc(-c2ccccc2)c1C=CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
NFKB1 P19838 1/20 0.53
CA4 P22748 1/20 0.53
PTGER3 P43115 4/20 0.51
PTGER2 P43116 4/20 0.51
PTGER1 P34995 3/20 0.51
PTGER4 P35408 3/20 0.49
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
BACE1 P56817 1/20 0.46
HDAC3 O15379 1/20 0.46
TNKS O95271 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2305914 0.87 PTPN1 (0.46) CA1CA2NFKB1CA4PTGER3
SCHEMBL181054 0.85 PTGER3 (0.66) CA1CA2NFKB1CA4PTGER3
SCHEMBL2433472 0.85 PTGER3 (0.66) CA1CA2NFKB1CA4PTGER3
Hydrochloric Acid SCHEMBL11527565 0.84 PTGER3 (0.64) CA1CA2NFKB1CA4PTGER3
SCHEMBL8746642 0.83 CA1 (0.61) CA1CA2NFKB1CA4PTGER3
SCHEMBL8746640 0.83 CA1 (0.61) CA1CA2NFKB1CA4PTGER3
SCHEMBL17802338 0.83 CA1 (0.53) CA1CA2NFKB1CA4PTGER3
SCHEMBL29454389 0.82 PTGER3 (0.58) CA1CA2NFKB1CA4PTGER3
SCHEMBL20545941 0.81 CA1 (0.51) CA1CA2NFKB1CA4PTGER3
SCHEMBL28368822 0.81 CA1 (0.51) CA1CA2NFKB1CA4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352061-B1 ORIENTATION FILM, LIQUID CRYSTAL DISPLAY HAVING ORIENTATION FILM, AND METHOD FOR FORMING ORIENTATION FILM SHARP KK (JP) 2015-01-07 EP disclosed
US-8597739-B2 Orientation film, liquid crystal display having orientation film, and method for forming orientation film SHARP KABUSHIKI KAISHA (JP) 2013-12-03 US disclosed
US-20110234955-A1 ORIENTATION FILM, LIQUID CRYSTAL DISPLAY HAVING ORIENTATION FILM, AND METHOD FOR FORMING ORIENTATION FILM SHARP KABUSHIKI KAISHA (JP) 2011-09-29 US disclosed
EP-2352061-A1 ORIENTATION FILM, LIQUID CRYSTAL DISPLAY HAVING ORIENTATION FILM, AND METHOD FOR FORMING ORIENTATION FILM Sharp Kabushiki Kaisha (JP) 2011-08-03 EP disclosed