Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479729 | 0.85 | MAPT (0.50) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28695257 | 0.85 | MAPT (0.50) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL23012890 | 0.84 | HDAC6 (0.49) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29479777 | 0.82 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL28711116 | 0.82 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL29479649 | 0.80 | PIK3CA (0.63) | HDAC6 | |
| SCHEMBL23012902 | 0.80 | PIK3CA (0.63) | HDAC6 | |
| SCHEMBL23012175 | 0.79 | NPC1 (0.70) | — | |
| SCHEMBL29479597 | 0.79 | NPC1 (0.70) | — | |
| SCHEMBL2242854 | 0.78 | MAPT (0.67) | HDAC6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |