Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711116 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL23012902 | 0.85 | PIK3CA (0.63) | KDM4ERAB9AALDH1A1MAPTRXFP1 | |
| SCHEMBL29479649 | 0.85 | PIK3CA (0.63) | KDM4ERAB9AALDH1A1MAPTRXFP1 | |
| SCHEMBL31165972 | 0.82 | PIK3CB (0.43) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL23012890 | 0.82 | HDAC6 (0.49) | SMN1; SMN2KDM4ERAB9AALDH1A1TP53 | |
| SCHEMBL23033958 | 0.82 | HDAC6 (0.55) | — | |
| SCHEMBL23012175 | 0.82 | NPC1 (0.70) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL29479597 | 0.82 | NPC1 (0.70) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL23033684 | 0.81 | HPSE (0.42) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 | |
| SCHEMBL29479679 | 0.81 | HPSE (0.42) | SMN1; SMN2KDM4ERAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |