Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 9/20 | 0.67 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL657830 | 0.99 | PRKCZ (0.66) | PRKCZPIN1ALDH1A1CHRM1KDM4E | |
| SCHEMBL2303477 | 0.91 | PRKCZ (0.80) | PRKCZPIN1 | |
| SCHEMBL2302318 | 0.90 | PRKCZ (0.67) | PRKCZPIN1CHRM1KDM4EHTT | |
| SCHEMBL2303557 | 0.89 | PRKCZ (0.84) | PRKCZPIN1KDM4E | |
| Hydrochloric Acid SCHEMBL659490 | 0.89 | PRKCZ (0.66) | PRKCZPIN1CHRM1KDM4E | |
| Hydrochloric Acid SCHEMBL657562 | 0.88 | PRKCZ (0.82) | PRKCZPIN1KDM4E | |
| SCHEMBL2303024 | 0.88 | PRKCZ (0.66) | PRKCZPIN1CHRM1KDM4EITGB3 | |
| Hydrochloric Acid SCHEMBL657731 | 0.87 | PRKCZ (0.65) | PRKCZPIN1CHRM1KDM4E | |
| SCHEMBL3049275 | 0.86 | PRKCZ (0.85) | PRKCZPIN1 | |
| Hydrochloric Acid SCHEMBL3043514 | 0.85 | PRKCZ (0.83) | PRKCZPIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | claimed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | claimed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |