SCHEMBL23034832

SCHEMBL23034832

Cc1cc(C2(c3ccc(OC(=O)Oc4ccccc4)c(C)c3)c3ccccc3-c3ccccc32)ccc1COC(=O)Oc1ccc(C2(c3ccc(OC(=O)Oc4ccccc4)c(C)c3)c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
HSD17B10 Q99714 2/20 0.33
HTT P42858 1/20 0.33
GFER P55789 1/20 0.33
MAPT P10636 3/20 0.32
POLB P06746 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TYMS P04818 1/20 0.32
HPGD P15428 2/20 0.31
FFAR1 O14842 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CHRM5 P08912 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23034831 0.95 ESR1 (0.53) ESR1ESR2MEN1KMT2AHSD17B10
SCHEMBL23034833 0.90 ESR1 (0.52) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL23034830 0.88 ESR1 (0.60) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL23034829 0.85 ESR1 (0.64) ESR1ESR2MEN1KMT2AHSD17B10
SCHEMBL16379089 0.75 ESR1 (0.40) ESR1ESR2MAPTL3MBTL1CHRM5
SCHEMBL15893582 0.75 ESR1 (0.37) ESR1ESR2CHRM5
SCHEMBL15893583 0.74 PPARA (0.38) ESR1ESR2CHRM5
SCHEMBL26257700 0.73 ESR1 (0.56) ESR1ESR2MEN1KMT2AHTT
SCHEMBL15893592 0.73 ESR1 (0.39) ESR1ESR2MEN1KMT2AHTT
SCHEMBL15356193 0.73 ESR1 (0.48) ESR1ESR2MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118009-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-14 US disclosed
US-20210054142-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-02-25 US disclosed