SCHEMBL23034833

SCHEMBL23034833

Cc1cc(C2(c3ccc(OC(=O)Oc4ccccc4)c(C)c3)c3ccccc3-c3ccccc32)ccc1OC(=O)Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
POLB P06746 3/20 0.37
HPGD P15428 1/20 0.36
MAPT P10636 5/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
OPRK1 P41145 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
XBP1 P17861 1/20 0.35
CHRM5 P08912 4/20 0.34
THRB P10828 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23034829 0.94 ESR1 (0.64) ESR1ESR2KMT2AMEN1POLB
SCHEMBL23034832 0.90 ESR1 (0.43) ESR1ESR2KMT2AMEN1POLB
SCHEMBL23034831 0.86 ESR1 (0.53) ESR1ESR2KMT2AMEN1POLB
SCHEMBL16379089 0.81 ESR1 (0.40) ESR1ESR2MAPTNPSR1L3MBTL1
SCHEMBL15893592 0.81 ESR1 (0.39) ESR1ESR2KMT2AMEN1MAPT
SCHEMBL15356193 0.81 ESR1 (0.48) ESR1ESR2KMT2AMEN1POLB
SCHEMBL15356188 0.81 ESR1 (0.48) ESR1ESR2KMT2AMEN1POLB
SCHEMBL4953713 0.81 ESR1 (0.54) ESR1ESR2KMT2AMEN1POLB
SCHEMBL21405721 0.80 ESR1 (0.50) ESR1ESR2KMT2AMEN1POLB
SCHEMBL21405722 0.80 ESR1 (0.50) ESR1ESR2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118009-B2 Aromatic polycarbonate oligomer solid HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-14 US disclosed
US-20210054142-A1 AROMATIC POLYCARBONATE OLIGOMER SOLID HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2021-02-25 US disclosed