Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 15/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.53 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094480 | 0.85 | HSD17B10 (0.52) | PARP10PARP15KMT2AALDH1A1CA1 | |
| SCHEMBL28073273 | 0.81 | MAPT (0.47) | PARP10KMT2AALDH1A1ELANERECQL | |
| SCHEMBL28216941 | 0.81 | PARP10 (0.57) | PARP10PARP15KMT2APARP4ALDH1A1 | |
| SCHEMBL26698255 | 0.79 | KMT2A (0.70) | PARP10PARP15KMT2APARP4ALDH1A1 | |
| SCHEMBL7190278 | 0.79 | MAPT (0.48) | KMT2AALDH1A1CA2ELANERECQL | |
| SCHEMBL475526 | 0.78 | CYP19A1 (0.52) | KMT2AALDH1A1ELANEMAPTHSD17B10 | |
| SCHEMBL25348271 | 0.78 | PARP10 (0.66) | PARP10PARP15KMT2APARP4ALDH1A1 | |
| SCHEMBL4564561 | 0.78 | KMT2A (0.56) | PARP10PARP15KMT2APARP4ALDH1A1 | |
| SCHEMBL19924536 | 0.77 | HTT (0.57) | KMT2AALDH1A1CA1CA2SMN1; SMN2 | |
| SCHEMBL20476548 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1SMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156411-B1 | ARTIFICIAL CATALYST SYSTEM CAPABLE OF SUBSTITUTING FOR IN VIVO ACYLATION FUNCTION | UNIV TOKYO (JP) | 2021-03-03 | — | — | EP | claimed |